Pesquisa sobre: AUTOPHAGY-RELATED PROTEIN-1 HOMOLOG 
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Descritor Inglês:   Autophagy-Related Protein-1 Homolog 
Descritor Espanhol:   homólogo de la proteína 1 relacionada con la autofagia 
Descritor Português:   Proteína Homóloga à Proteína-1 Relacionada à Autofagia 
Sinônimos Inglês:   Autophagy Related Protein 1 Homolog
Serine Threonine Protein Kinase ULK1
Serine-Threonine Protein Kinase ULK1
ULK1 Protein
Unc 51 Like Autophagy Activating Kinase 1
Unc 51 Like Kinase 1
Unc-51 Like Autophagy Activating Kinase 1
Unc-51-Like Kinase 1  
Categoria:   D08.811.913.696.620.682.700.108
D12.644.360.081
D12.776.094.438
D12.776.476.078
Definição Inglês:   A serine/threonine-protein kinase that functions in AUTOPHAGY in response to starvation. It acts on the PHOSPHATIDYLINOSITOL 3-KINASE complex PIK3C3 to regulate AUTOPHAGOSOME formation. It also functions as both a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) and is activated by AMPK, which it also negatively regulates. 
Nota Histórica Inglês:   2017 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número do Registro:   56509 
Identificador Único:   D000071189 

Ocorrência na BVS:
 

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